AZD9150, a next-generation antisense oligonucleotide inhibitor of STAT3 with early evidence of clinical activity in lymphoma and lung cancer
…, N Fowler, T Zhou, J Schmidt, M Jo, SJ Lee… - Science translational …, 2015 - science.org
Next-generation sequencing technologies have greatly expanded our understanding of
cancer genetics. Antisense technology is an attractive platform with the potential to translate …
cancer genetics. Antisense technology is an attractive platform with the potential to translate …
Framing financial incentives to increase physical activity among overweight and obese adults: a randomized, controlled trial
…, S Sproat, C Hyson, N Haff, SM Lee… - Annals of internal …, 2016 - acpjournals.org
Background: Financial incentive designs to increase physical activity have not been well-examined.
Objective: To test the effectiveness of 3 methods to frame financial incentives to …
Objective: To test the effectiveness of 3 methods to frame financial incentives to …
[HTML][HTML] Volatile organic compounds emitted by Trichoderma species mediate plant growth
S Lee, M Yap, G Behringer, R Hung… - Fungal biology and …, 2016 - Springer
Background Many Trichoderma species are applied as biofungicides and biofertilizers to
agricultural soils to enhance crop growth. These filamentous fungi have the ability to reduce …
agricultural soils to enhance crop growth. These filamentous fungi have the ability to reduce …
Hypoxia-induced pathological angiogenesis mediates tumor cell dissemination, invasion, and metastasis in a zebrafish tumor model
Mechanisms underlying pathological angiogenesis in relation to hypoxia in tumor invasion
and metastasis remain elusive. Here, we have developed a zebrafish tumor model that …
and metastasis remain elusive. Here, we have developed a zebrafish tumor model that …
Fungal volatile organic compounds and their role in ecosystems
R Hung, S Lee, JW Bennett - Applied microbiology and biotechnology, 2015 - Springer
All odorants are volatile organic compounds (VOCs), ie, low molecular weight compounds
that easily evaporate at normal temperatures and pressure. Fungal VOCs are relatively …
that easily evaporate at normal temperatures and pressure. Fungal VOCs are relatively …
Arabidopsis thaliana as a model system for testing the effect of Trichoderma volatile organic compounds
R Hung, S Lee, JW Bennett - Fungal ecology, 2013 - Elsevier
In ecosystems, plant and bacterial volatile organic compounds (VOCs) are known to influence
plant growth but less is known about the physiological effects of fungal VOCs. We have …
plant growth but less is known about the physiological effects of fungal VOCs. We have …
[HTML][HTML] STAT3 antisense oligonucleotide AZD9150 in a subset of patients with heavily pretreated lymphoma: results of a phase 1b trial
…, Q Liu, T Zhou, J Schmidt, M Jo, SJ Lee… - … for immunotherapy of …, 2018 - Springer
Background The Janus kinase (JAK) and signal transduction and activation of transcription (STAT)
signaling pathway is an attractive target in multiple cancers. Activation of the JAK-…
signaling pathway is an attractive target in multiple cancers. Activation of the JAK-…
[HTML][HTML] Individual versus team-based financial incentives to increase physical activity: a randomized, controlled trial
…, K Eberbach, KJ Walters, N Haff, SM Lee… - Journal of general …, 2016 - Springer
BACKGROUND More than half of adults in the United States do not attain the minimum
recommended level of physical activity to achieve health benefits. The optimal design of financial …
recommended level of physical activity to achieve health benefits. The optimal design of financial …
An operant social self-administration and choice model in mice
Little is known about how social factors contribute to neurobiology or neuropsychiatric
disorders. The use of mice allows one to probe the neurobiological bases of social interaction, …
disorders. The use of mice allows one to probe the neurobiological bases of social interaction, …
Incidence and progression of myopia in early adulthood
SSY Lee, G Lingham, PG Sanfilippo… - JAMA …, 2022 - jamanetwork.com
Importance Myopia incidence and progression has been described extensively in children.
However, few data exist regarding myopia incidence and progression in early adulthood. …
However, few data exist regarding myopia incidence and progression in early adulthood. …