Are randomized clinical trials good for us (in the short term)? Evidence for a “trial effect”

DA Braunholtz, SJL Edwards, RJ Lilford - Journal of clinical epidemiology, 2001 - Elsevier
Objective: To assess whether there is evidence that randomized controlled trials are
systematically beneficial, or harmful, for patients. In other words, is there a “trial effect”? If so, to …

Applications of biofilms in bioremediation and biotransformation of persistent organic pollutants, pharmaceuticals/personal care products, and heavy metals

SJ Edwards, BV Kjellerup - Applied microbiology and biotechnology, 2013 - Springer
In this review, the strategies being employed to exploit the inherent durability of biofilms and
the diverse nutrient cycling of the microbiome for bioremediation are explored. Focus will be …

Ethical issues in the design and conduct of cluster randomised controlled trials

SJL Edwards, DA Braunholtz, RJ Lilford, AJ Stevens - Bmj, 1999 - bmj.com
In most randomised controlled trials, individual patients are randomised to a treatment or
control group, but sometimes this is undesirable or even impossible and groups (clusters) of …

[PDF][PDF] Interleukin-17A serves a priming role in autoimmunity by recruiting IL-1β-producing myeloid cells that promote pathogenic T cells

AM McGinley, CE Sutton, SC Edwards, CM Leane… - Immunity, 2020 - cell.com
Interleukin-17A (IL-17A) is a major mediator of tissue inflammation in many autoimmune
diseases. Anti-IL-17A is an effective treatment for psoriasis and is showing promise in clinical …

The ethics of randomised controlled trials from the perspectives of patients, the public, and healthcare professionals

SJL Edwards, RJ Lilford, J Hewison - Bmj, 1998 - bmj.com
Methods To find out what patients, the general public, and healthcare professionals thought
about trials, we undertook a review of the ethics of randomised controlled trials from these …

Medicinal plants used in the traditional management of diabetes and its sequelae in Central America: A review

P Giovannini, MJR Howes, SE Edwards - Journal of ethnopharmacology, 2016 - Elsevier
Ethnopharmacological relevance Globally 387 million people currently have diabetes and it
is projected that this condition will be the 7th leading cause of death worldwide by 2030. As …

Tumor characteristics associated with mammographic detection of breast cancer in the Ontario breast screening program

VA Kirsh, AM Chiarelli, SA Edwards… - Journal of the …, 2011 - academic.oup.com
Background Few studies have compared the prognostic value of tumor characteristics by type
of breast cancer diagnosed in the interval between mammographic screenings with screen…

[BOOK][B] Phytopharmacy: An evidence-based guide to herbal medicinal products

SE Edwards, I da Costa Rocha, EM Williamson… - 2015 - books.google.com
Healthcare professionals, including doctors, pharmacists and nurses, are often confronted
with patients who use over-the-counter (OTC) herbal medicinal products and food …

[HTML][HTML] PD-1 and TIM-3 differentially regulate subsets of mouse IL-17A–producing γδ T cells

SC Edwards, A Hedley, WHM Hoevenaar… - Journal of Experimental …, 2023 - rupress.org
IL-17A–producing γδ T cells in mice consist primarily of Vγ6+ tissue-resident cells and Vγ4+
circulating cells. How these γδ T cell subsets are regulated during homeostasis and cancer …

Denying rape but endorsing forceful intercourse: Exploring differences among responders

SR Edwards, KA Bradshaw, VB Hinsz - Violence and Gender, 2014 - liebertpub.com
Sexual assault is a problem on many college campuses, and many researchers have
conducted studies assessing the prevalence of sexual assault perpetration and intentions to be …