Background. Opioids contribute to more than 60 000 deaths annually in North America.
While the expansion of overdose education and naloxone distribution (OEND) programs has …

Background— Less than one-third of smokers hospitalized with an acute coronary syndrome
(ACS) remain abstinent following discharge. We assessed whether varenicline, begun in-…

… B, Participants were considered continuously abstinent if they reported smoking 0 cigarettes
in the 7 days before each follow-up since randomization, with expired carbon monoxide …

Background— Designed to mimic the look and feel of tobacco cigarettes, electronic cigarettes
(e-cigarettes) may facilitate smoking cessation. However, the efficacy and safety of e-…

Electronic cigarette (e-cigarette) use has risen to unprecedented levels among youth in the
United States. In this review, we discuss the patterns of use underlying the current youth …

Importance Stent retrievers are a promising alternative for the treatment of acute ischemic
stroke (AIS). Several recently completed clinical trials have examined the use of stent …

Background Varenicline is an efficacious smoking‐cessation drug. However, previous meta‐analyses
provide conflicting results regarding its cardiovascular safety. The publication of …

Introduction There is substantial debate concerning the impact of cannabis decriminalization
and legalization on road safety outcomes. Methods Seven databases were systematically …

Background: Cholesteryl ester transfer protein (CETP) inhibitors increase serum high-density
lipoprotein cholesterol (HDL-c) concentration; however, their impact on cardiovascular …

Background: With the recent legalization of recreational cannabis in Canada, cannabis-impaired
driving is an important public safety concern. Our aim was to examine the association …