Despite evidence that the intestinal microbiota (IM) is involved in the pathogenesis of obesity,
the IM composition of patients with nonalcoholic fatty liver disease (NAFLD) has not been …

BACKGROUND: The incidence and risk factors for adefovir-resistant HBV have not been
clearly defined. AIMS: To characterize the virologic response to adefovir, to determine the rate …

Multi‐drug resistant hepatitis B virus (HBV) has been reported in hepatitis B patients who
received sequential antiviral therapy. In vitro studies showed that HBV constructs with …

In nonalcoholic fatty liver disease, hepatic gene expression and fatty acid (FA) composition
have been reported independently, but a comprehensive gene expression profiling in …

… Dr SK Fung reports receiving consultancy fees from Gilead Sciences, Merck, and Bristol …
JF Flaherty, GM Subramanian, GR Foster, and K. Agarwal contributed to the conception and …

H epatitis B virus (HBV) has been classified into 8 genotypes (AH) based on an intergroup
divergence of 8% or more in the complete nucleotide sequence.'J Figure 1 illustrates the …

BACKGROUND/AIMS: The susceptibility of adefovir-resistant hepatitis B virus (HBV) mutants
is only reduced by 3–10-fold in in vitro studies, suggesting that virologic breakthrough and …

Lamivudine has demonstrated efficacy for the treatment of hepatitis B e antigen‐negative
chronic hepatitis B (e‐CHB). However, treatment withdrawal after 1 year has been associated …

Chronic hepatitis B (CHB) is a dynamic disease that is influenced by host and virological
factors. The management of CHB has become more complex with the increasing use of long-…

… Scott K. Fung reports receiving fees for speaking and teaching and/or serving on advisory
… Man-Fung Yuen reports being an advisor/consultant for and/or having received grant/…