Objective To compare the effects of treatments for coronavirus disease 2019 (covid-19).
Design Living systematic review and network meta-analysis. Data sources WHO covid-19 …

Background Despite advances in defibrillation technology, shock-refractory ventricular
fibrillation remains common during out-of-hospital cardiac arrest. Double sequential external …

When direct and indirect estimates of treatment effects are coherent, network meta-analysis (NMA)
estimates should have increased precision (narrower confidence or credible intervals …

Federated learning (FL) is a method used for training artificial intelligence models with data
from multiple sources while maintaining data anonymity, thus removing many barriers to data …

Background Development of clinical practice guidelines involves making trade-offs between
desirable and undesirable consequences of alternative management strategies. Although …

Purpose Targeted temperature management (TTM) may improve survival and functional
outcome in comatose survivors of out-of-hospital cardiac arrest (OHCA), though the optimal …

Updates This is the second version (first update) of the living systematic review, replacing the
previous version (available as a data supplement). When citing this paper please consider …

STUDY: objective: The primary objective is to compare total sedation time when ketamine-propofol
is used compared with ketamine alone for pediatric procedural sedation and …

Background Time to treatment is critical for survival from sudden cardiac arrest. Every
minute delay in defibrillation results in a 7% to 10% reduction in survival. This is particularly …

The impact of transfusing fresher vs older red blood cells (RBCs) on patient-important outcomes
remains controversial. Two recently published large trials have provided new evidence. …