Background Obesity is a major risk factor for cardiovascular disease, but the most predictive
measure for different ethnic populations is not clear. We aimed to assess whether markers of …

This two-part article provides an overview of the global burden of atherothrombotic cardiovascular
disease. Part I initially discusses the epidemiologic transition which has resulted in a …

Background— Although preventive drug therapy is a priority after acute coronary syndrome,
less is known about adherence to behavioral recommendations. The aim of this study was to …

Background We evaluated whether rivaroxaban alone or in combination with aspirin would
be more effective than aspirin alone for secondary cardiovascular prevention. Methods In this …

We performed a meta-analysis of 14 genome-wide association studies of coronary artery
disease (CAD) comprising 22,233 individuals with CAD (cases) and 64,762 controls of …

Background High plasma HDL cholesterol is associated with reduced risk of myocardial
infarction, but whether this association is causal is unclear. Exploiting the fact that genotypes are …

Background Although a wealth of literature links dietary factors and coronary heart disease (CHD),
the strength of the evidence supporting valid associations has not been evaluated …

Abbreviations: ACT activated clotting time; APTT activated partial thromboplastin time; AT
antithrombin; AT-III antithrombin III; CI confidence interval; DVT deep vein thrombosis; GP …

Objective To systematically review associations between intake of saturated fat and trans
unsaturated fat and all cause mortality, cardiovascular disease (CVD) and associated mortality, …

Background— The use of multiple antithrombotic drugs and aggressive invasive strategies
has increased the risk of major bleeding in acute coronary syndrome (ACS) patients. It is not …