Apolipoprotein E (APOE) is the strongest genetic risk factor for Alzheimer's disease (AD).
Previous studies suggest that the effect of apoE on amyloid-β (Aβ) accumulation plays a major …

Importance Motor vehicle crashes (MVCs) are a leading public health concern. Emergency
medical service (EMS) response time is a modifiable, system-level factor with the potential to …

fMRI was used to investigate the separate influences of orthographic, phonological, and
semantic processing on the ability to learn new words and the cortical circuitry recruited to …

Background Patients with severe traumatic brain injury (sTBI) are at high risk for developing
venous thromboembolism (VTE). Nonetheless, pharmacologic VTE prophylaxis is often …

Objective: We set out to compare the incidence of bowel repair and/or resection in a large
cohort of patients with adhesive small bowel obstruction (SBO) managed operatively. …

Importance Adhesive small-bowel obstruction (aSBO) is a potentially chronic, recurring
surgical illness. Although guidelines suggest trials of nonoperative management, the long-term …

Objective: To estimate long-term mortality following major burn injury compared with matched
controls. Summary Background Data: The effect of sustaining a major burn injury on long-…

BACKGROUND Pulmonary embolism (PE) is a leading cause of delayed mortality in patients
with severe injury. While low-molecular-weight heparin (LMWH) is often favored over …

BACKGROUND Burn-related mortality has decreased significantly over the past several
decades. Although often attributed in part to regionalization of burn care, this has not been …

Objective: To determine whether restrictive fluid resuscitation results in increased rates of
acute kidney injury (AKI) or infectious complications. Background: Studies demonstrate that …