Type 1 diabetes (T1D) in children results from autoimmune destruction of pancreatic beta
cells, leading to insufficient production of insulin 1 . A number of genetic determinants of T1D …

OBJECTIVE—Two recent genome-wide association (GWA) studies have revealed novel loci
for type 1 diabetes, a common multifactorial disease with a strong genetic component. To …

OBJECTIVE—In stage 1 of our genome-wide association (GWA) study for type 1 diabetes,
one locus at 16p13 was detected (P = 1.03 × 10 −10 ) and confirmed in two additional cohorts. …

Context: To date, 16 IGFALS mutations in 21 patients with acid-labile subunit (ALS) deficiency
have been reported. The impact of heterozygosity for IGFALS mutations on growth is …

Context: KISS1 is a candidate gene for GnRH deficiency. Objective: Our objective was to
identify deleterious mutations in KISS1. Patients and Methods: DNA sequencing and …

To determine if pump therapy with continuous glucose monitoring offering low glucose
suspend (LGS) decreases fear of hypoglycemia among children with type 1 diabetes and their …

Six children with mild cerebral palsy (CP) entered a study of overnight low-intensity
transcutaneous electrical stimulation (ES) to the leg muscles. After 6 months, statistically significant …

OBJECTIVE To describe celiac disease (CD) screening rates and glycemic outcomes of a
gluten-free diet (GFD) in patients with type 1 diabetes who are asymptomatic for CD. …

Motor unit number estimation (MUNE) was applied to the biceps brachii muscles of 13 young
patients (age 5–24 years) with spinal muscular atrophy (SMA) and the results compared …

Background: The 2′,5′-oligoadenylate synthetase genes (OAS1, OAS2, and OAS3) map
to human chromosome 12q24 and encode a family of enzymes pivotal to innate antiviral …