Background Sodium-glucose cotransporter-2 inhibitors (SGLT2i) and glucagon-like peptide-1
receptor agonists (GLP-1RA) have shown benefits in patients with diabetes and …

High-quality data are fundamental to healthcare research, future applications of artificial
intelligence and advancing healthcare delivery and outcomes through a learning health system. …

OBJECTIVE: Adequate iodine intake in pregnancy is essential for fetal neurodevelopment.
Thirty-two percent of non-pregnant Canadian women of childbearing age were reported to …

In animal studies, the combination of in utero fluoride exposure and low iodine has greater
negative effects on offspring learning and memory than either alone, but this has not been …

Background: The Edmonton Obesity Staging System (EOSS) combined with body mass
index (BMI) enables improved functional and prognostic assessment for patients. To facilitate …

Background Prenatal fluoride exposure can have adverse effects on children’s development;
however, associations with visual and cardiac autonomic nervous system functioning are …

Objectives: To examine the trends in cannabis use within 30 days of first admission to
inpatient psychiatry in Ontario, Canada, between 2007 and 2017, and the characteristics of …

Background Linked electronic medical records and administrative data have the potential to
support a learning health system and data-driven quality improvement. However, data …

Glycans form a highly variable constituent of our mucosal surfaces and profoundly affect our
susceptibility to infection and disease. The diversity and importance of these surface …

Background Stratifying risk of postoperative pulmonary complications after major abdominal
surgery allows clinicians to modify risk through targeted interventions and enhanced …