Safer injection facilities provide medical supervision for illicit drug injections. We aimed to
examine factors associated with syringe sharing in a community-recruited cohort of illicit …

Background Overdose from illicit drugs is a leading cause of premature mortality in North
America. Internationally, more than 65 supervised injecting facilities (SIFs), where drug users …

In September, 2015, the member states of the UN endorsed Sustainable Development Goals
(SDGs) for 2030, which aspire to human-rights-centred approaches to ensuring the health …

Background: North America's first medically supervised safer injecting facility for illicit injection
drug users was opened in Vancouver on Sept. 22, 2003. Although similar facilities exist in …

The catabolism of cholesterol into bile acids is regulated by oxysterols and bile acids, which
induce or repress transcription of the pathway's rate-limiting enzyme cholesterol 7α-…

Violence is amongst the primary concerns of communities around the world and research has
demonstrated links between violence and the illicit drug trade, particularly in urban settings…

BACKGROUND: Non-fatal overdose is a major determinant of morbidity among injection drug
users (IDU). We sought to evaluate factors associated with non-fatal overdose among IDU …

Background Results of cohort studies and mathematical models have suggested that
increased coverage with highly active antiretroviral therapy (HAART) could reduce HIV …

Long-duration γ-ray bursts (GRBs) are thought to result from the explosions of certain massive
stars 1 , and some are bright enough that they should be observable out to redshifts of z > …

Continuing expansion of the HIV/AIDS pandemic has been recognised as an exceptional
challenge to global health, international development, and world security. UNAIDS estimates …