Background Studies that have evaluated the use of intravenous vitamin C in adults with
sepsis who were receiving vasopressor therapy in the intensive care unit (ICU) have shown …

Early mobilization of critically ill patients is beneficial, suggesting that it should be incorporated
into daily clinical practice. Early passive, active, and combined progressive mobilizations …

Background The lack of a reliable scoring system that predicts the development of septic shock
and death precludes comparison of disease and/or treatment outcomes in animal models …

With the development of new immunosuppressive agents, the focus of anti-rejection therapy
has shifted from prevention of acute allograft rejection to an emphasis on sufficient …

Myocardial contractile dysfunction in sepsis is associated with the increased morbidity and
mortality. Although the underlying mechanisms of the cardiac depression have not been fully …

Septic acute kidney injury (AKI) and myocardial dysfunction are leading causes of mortality
with no accepted method of therapy. In this study we demonstrate the role of growth …

Recombinant human growth differentiation factor 15 (rhGDF15) affects dendritic cell (DC)
maturation. However, whether GDF15 is expressed in DCs and its roles and signaling in DCs …

Mucosa-associated invariant T (MAIT) cells are innate-like T lymphocytes that are unusually
abundant in the human liver, a common site of colorectal carcinoma (CRC) metastasis. …

Ischemia reperfusion (I/R) injury which inevitably occurs during heart transplantation is the
major factor leading to organ failure and graft rejection. In order to develop new therapies to …

Although up to 60% of the population at any one time carry Staphylococcus aureus (S. aureus)
without significant clinical consequences, infections by S. aureus are a major health care …