[HTML][HTML] Bacterial co-infection and secondary infection in patients with COVID-19: a living rapid review and meta-analysis

BJ Langford, M So, S Raybardhan, V Leung… - Clinical microbiology …, 2020 - Elsevier
Background Bacterial co-pathogens are commonly identified in viral respiratory infections
and are important causes of morbidity and mortality. The prevalence of bacterial infection in …

[HTML][HTML] Antibiotic prescribing in patients with COVID-19: rapid review and meta-analysis

BJ Langford, M So, S Raybardhan, V Leung… - Clinical microbiology …, 2021 - Elsevier
Background The proportion of patients infected with SARS-CoV-2 that are prescribed
antibiotics is uncertain, and may contribute to patient harm and global antibiotic resistance. …

[HTML][HTML] Antibiotic resistance associated with the COVID-19 pandemic: a systematic review and meta-analysis

BJ Langford, JPR Soucy, V Leung, M So… - Clinical Microbiology …, 2023 - Elsevier
Background COVID-19 and antimicrobial resistance (AMR) are two intersecting global public
health crises. Objective We aimed to describe the impact of the COVID-19 pandemic on …

[HTML][HTML] Antimicrobial resistance in patients with COVID-19: a systematic review and meta-analysis

BJ Langford, M So, M Simeonova, V Leung, J Lo… - The Lancet …, 2023 - thelancet.com
Background Frequent use of antibiotics in patients with COVID-19 threatens to exacerbate
antimicrobial resistance. We aimed to establish the prevalence and predictors of bacterial …

[HTML][HTML] Predictors and microbiology of respiratory and bloodstream bacterial infection in patients with COVID-19: living rapid review update and meta-regression

…, V Leung, S Raybardhan, J Lo, T Kan, F Leung… - Clinical Microbiology …, 2022 - Elsevier
Background The prevalence of bacterial infection in patients with COVID-19 is low, however,
empiric antibiotic use is high. Risk stratification may be needed to minimize unnecessary …

[HTML][HTML] Estimating daily antibiotic harms: an umbrella review with individual study meta-analysis

J Curran, J Lo, V Leung, K Brown, KL Schwartz… - Clinical Microbiology …, 2022 - Elsevier
Background There is growing evidence supporting the efficacy of shorter courses of antibiotic
therapy for common infections. However, the risks of prolonged antibiotic duration are …

Effect of antibiotic-prescribing feedback to high-volume primary care physicians on number of antibiotic prescriptions: a randomized clinical trial

…, M Taljaard, D Neish, KA Brown, V Leung… - JAMA Internal …, 2021 - jamanetwork.com
Importance Antibiotic overuse contributes to adverse drug effects, increased costs, and
antimicrobial resistance. Objective To evaluate peer-comparison audit and feedback to high-…

Unnecessary antibiotic prescribing in a Canadian primary care setting: a descriptive analysis using routinely collected electronic medical record data

…, K Tu, E Candido, J Johnstone, V Leung… - … Open Access Journal, 2020 - cmajopen.ca
Background: Unnecessary antibiotic use in the community in Canada is not well defined.
Our objective was to quantify unnecessary antibiotic prescribing in a Canadian primary care …

The impact of COVID-19 on outpatient antibiotic prescriptions in Ontario, Canada; an interrupted time series analysis

…, BJ Langford, V Leung, M So, E Leung… - Open Forum …, 2021 - academic.oup.com
Background The coronavirus disease 2019 (COVID-19) pandemic has potentially impacted
outpatient antibiotic prescribing. Investigating this impact may identify stewardship …

Community pharmacist prescribing of antimicrobials: A systematic review from an antimicrobial stewardship perspective

…, KL Schwartz, G Garber, V Leung - … Journal/Revue des …, 2021 - journals.sagepub.com
Background: Pharmacist prescribing authority is expanding, while antimicrobial resistance
is an increasing global concern. We sought to synthesize the evidence for antimicrobial …