Importance Little is known about the relationship between perioperative high-sensitivity
troponin T (hsTnT) measurements and 30-day mortality and myocardial injury after noncardiac …

The Canadian Cardiovascular Society Guidelines Committee and key Canadian opinion
leaders believed there was a need for up to date guidelines that used the Grading of …

Background Perioperative bleeding is common in patients undergoing noncardiac surgery.
Tranexamic acid is an antifibrinolytic drug that may safely decrease such bleeding. Methods …

BACKGROUND: The incidence, severity, and duration of postoperative oxygen desaturation
in the general surgical population are poorly characterized. We therefore used continuous …

Background Myocardial injury after non-cardiac surgery (MINS) increases the risk of
cardiovascular events and deaths, which anticoagulation therapy could prevent. Dabigatran …

Background The effect on cardiovascular outcomes of withholding angiotensin-converting
enzyme inhibitors or angiotensin II receptor blockers in chronic users before noncardiac …

Background Observational studies have suggested that accelerated surgery is associated
with improved outcomes in patients with a hip fracture. The HIP ATTACK trial assessed …

Background: Among patients having noncardiac surgery, perioperative hemodynamic
abnormalities are associated with vascular complications. Uncertainty remains about what …

Objectives To determine if coronary computed tomographic angiography enhances prediction
of perioperative risk in patients before non-cardiac surgery and to assess the preoperative …

Background: Uncertainty remains about the effects of aspirin in patients with prior percutaneous
coronary intervention (PCI) having noncardiac surgery. Objective: To evaluate benefits …