User profiles for Vincent C. Tam

Vincent C. Tam

Center for Infectious Disease Research
Verified email at seattlebiomed.org
Cited by 6255

Tremelimumab plus durvalumab in unresectable hepatocellular carcinoma

…, V Breder, A Vasilyev, A Heurgué, VC Tam… - NEJM …, 2022 - evidence.nejm.org
Background A single, high priming dose of tremelimumab (anti-cytotoxic T lymphocyte–associated
antigen 4) plus durvalumab (anti–programmed cell death ligand-1), an infusion …

Frequency, type and clinical importance of medication history errors at admission to hospital: a systematic review

VC Tam, SR Knowles, PL Cornish, N Fine… - Cmaj, 2005 - Can Med Assoc
Background: Over a quarter of hospital prescribing errors are attributable to incomplete
medication histories being obtained at the time of admission. We undertook a systematic review …

Genomewide identification of proteins secreted by the Hrp type III protein secretion system of Pseudomonas syringae pv. tomato DC3000

…, DJ Schneider, VC Tam… - Proceedings of the …, 2002 - National Acad Sciences
The ability of Pseudomonas syringae pv. tomato DC3000 to be pathogenic on plants depends
on the Hrp (hypersensitive response and pathogenicity) type III protein secretion system …

[HTML][HTML] Lipidomic profiling of influenza infection identifies mediators that induce and resolve inflammation

VC Tam, O Quehenberger, CM Oshansky, R Suen… - Cell, 2013 - cell.com
Bioactive lipid mediators play a crucial role in the induction and resolution of inflammation.
To elucidate their involvement during influenza infection, liquid chromatography/mass …

Genomic characterization of non-O1, non-O139 Vibrio cholerae reveals genes for a type III secretion system

M Dziejman, D Serruto, VC Tam… - Proceedings of the …, 2005 - National Acad Sciences
Non-O1, non-O139 Vibrio cholerae can cause gastroenteritis and extraintestinal infections,
but, unlike O1 and O139 strains of V. cholerae, little is known about the virulence gene …

[HTML][HTML] A type III secretion system in Vibrio cholerae translocates a formin/spire hybrid-like actin nucleator to promote intestinal colonization

VC Tam, D Serruto, M Dziejman, W Brieher… - Cell host & …, 2007 - cell.com
We have previously characterized a non-O1, non-O139 Vibrio cholerae strain, AM-19226,
that lacks the known virulence factors but contains components of a type III secretion system (…

The Pseudomonas syringae type III‐secreted protein HopPtoD2 possesses protein tyrosine phosphatase activity and suppresses programmed cell death in plants

A Espinosa, M Guo, VC Tam, ZQ Fu… - Molecular …, 2003 - Wiley Online Library
The bacterial plant pathogen Pseudomonas syringae possesses a type III protein secretion
system that delivers many virulence proteins into plant cells. A subset of these proteins (…

Assessment of treatment with sorafenib plus doxorubicin vs sorafenib alone in patients with advanced hepatocellular carcinoma: phase 3 CALGB 80802 randomized …

…, R Goel, PE Lammers, TS Bekaii-Saab, VC Tam… - JAMA …, 2019 - jamanetwork.com
Importance Previous communication has reported significant improvement in overall survival
(OS) when using doxorubicin plus sorafenib in the treatment of advanced hepatocellular …

Serum alpha-fetoprotein levels and clinical outcomes in the phase III CELESTIAL study of cabozantinib versus placebo in patients with advanced hepatocellular …

…, JW Park, T Yau, SL Chan, JF Blanc, VC Tam… - Clinical Cancer …, 2020 - AACR
Purpose: The phase III CELESTIAL study demonstrated improved overall survival (OS) and
progression-free survival (PFS) with cabozantinib versus placebo in patients with previously …

Lipidomic profiling of bioactive lipids by mass spectrometry during microbial infections

VC Tam - Seminars in immunology, 2013 - Elsevier
Bioactive lipid mediators play crucial roles in promoting the induction and resolution of
inflammation. Eicosanoids and other related unsaturated fatty acids have long been known to …