Prevalence and incidence of Huntington's disease: an updated systematic review and meta‐analysis

A Medina, Y Mahjoub, L Shaver… - Movement …, 2022 - Wiley Online Library
The incidence and prevalence of Huntington's disease (HD) based on a systematic review
and meta‐analysis of 20 studies published from 1985 to 2010 was estimated at 0.38 per …

Iron in multiple sclerosis: roles in neurodegeneration and repair

E Stephenson, N Nathoo, Y Mahjoub, JF Dunn… - Nature Reviews …, 2014 - nature.com
MRI and histological studies have shown global alterations in iron levels in the brains of
patients with multiple sclerosis (MS), including increases in the iron stored by macrophages and …

Unexpected additive effects of minocycline and hydroxychloroquine in models of multiple sclerosis: Prospective combination treatment for progressive disease?

S Faissner, Y Mahjoub, M Mishra… - Multiple Sclerosis …, 2018 - journals.sagepub.com
Background: Most multiple sclerosis (MS) patients succumb to a progressive phenotype.
Continued lymphocyte activity in the brain, microglia-mediated injury, iron deposition, and …

[HTML][HTML] Quality of life, respiratory symptoms, and health care utilization 1 year following outpatient management of COVID-19: a prospective cohort study

…, R Mehta, G McLeod, M Wan, JD Krett, Y Mahjoub… - Scientific Reports, 2022 - nature.com
The long-term impact of COVID-19 among those with mild infections is not well characterized.
Among 81 adults who completed online assessments at 3- and 12-months following …

Patient-reported outcomes of neurologic and neuropsychiatric symptoms in mild COVID-19: a prospective cohort study

…, GA McLeod, MW Wan, JD Krett, Y Mahjoub… - … Open Access Journal, 2023 - cmajopen.ca
Background: Various neurologic manifestations have been reported in patients with COVID-19,
mostly in retrospective studies of patients admitted to hospital, but there are few data on …

A role for vessel‐associated extracellular matrix proteins in multiple sclerosis pathology

…, JL Watson, JI Spencer, G Niblett, Y Mahjoub… - Brain …, 2024 - Wiley Online Library
Multiple sclerosis (MS) is unsurpassed for its clinical and pathological hetherogeneity, but
the biological determinants of this variability are unknown. HLA‐DRB1*15, the main genetic …

Incidental intracranial pathology: a retrospective case review of structural neuroimaging results amongst young adult psychiatric patients

DB LeBaron, Y Mahjoub, A Abba-Aji - … Disease and Treatment, 2019 - Taylor & Francis
Objective: Given that there continue to be conflicting recommendations on the inclusion of
routine structural neuroimaging amongst the investigations ordered in psychiatric patients, our …

Immunology and microbiome: Implications for motor systems

Y Mahjoub, D Martino - Handbook of Clinical Neurology, 2023 - Elsevier
Immune-inflammatory mechanisms seem to play a relevant role in neurodegenerative
disorders affecting motor systems, particularly Parkinson's disease, where activity changes in …

Progressive vertebrobasilar vasculopathy and stroke secondary to giant cell arteritis

Y Mahjoub, ED McKenzie, S Raouf, M Almekhlafi - Stroke, 2022 - Am Heart Assoc
His history was significant for diabetes, prior smoking, and a remote nephrectomy for renal
cell carcinoma. Six months before presentation to our hospital, he had developed gradual-…

Kikuchi-Fujimoto disease preceding diagnosis of relapsing–remitting multiple sclerosis

Y Mahjoub, A Nickel, MD Wong… - Acta Neurologica …, 2023 - Springer
A 44-year-old woman was evaluated for two neurologic episodes. The first consisted of right
arm numbness and weakness lasting 2 months. Two months later, she developed right leg …