Cardiovascular disease (CVD) is the main cause of death globally and responsible for the
second highest number of deaths in Canada. Medical advancements in the treatment of …

Lay Summary The cost of heart failure care is high owing to the cost of hospitalization and
chronic treatments. Heart failure treatments vary in their benefit and cost. The cost …

Objectives: The authors investigated the impact of coronary artery bypass grafting (CABG)
on first and recurrent hospitalization in this population. Background: In the STICH (Surgical …

Background: Sacubitril/Valsartan has been shown to improve mortality and reduce
hospitalizations in patients with heart failure with reduced ejection fraction (HFrEF). The …

Cardiac fibrosis is a significant contributor to heart failure and is characterized by abnormal
ECM deposition and impaired contractile function. We have previously developed a model …

Aims The prognosis after hospitalization for acute decompensated heart failure (ADHF)
remains poor, especially< 30 days post‐discharge. Evidence‐based medications with …

Cardiomyopathies represent an important cause of heart failure, often affecting young
individuals, and have important implications for relatives. Genetic testing for …

Acute heart failure (AHF) is a complex, heterogeneous, clinical syndrome with high morbidity
and mortality, incurring significant health care costs. Patients transition from home to the …

Heart failure (HF) is a leading and growing cause of cardiovascular morbidity, mortality, and
health care use in Canada. 1 The disease is associated with marked impairment in both …

Heart failure (HF) is a global public health burden, characterized by frequent emergency
department (ED) visits and hospitalizations. Identifying successful strategies to avoid …