Preemptive panel-based pharmacogenetic testing: the time is now

KW Weitzel, LH Cavallari, LJ Lesko - Pharmaceutical research, 2017 - Springer
While recent discoveries have paved the way for the use of genotype-guided prescribing in
some clinical environments, significant debate persists among clinicians and researchers …

Pharmacogenomic testing to support prescribing in primary care: a structured review of implementation models

J Hayward, J McDermott, N Qureshi… - …, 2021 - Future Medicine
The application of pharmacogenomics could meaningfully contribute toward medicines
optimization within primary care. This review identified 13 studies describing eight …

[HTML][HTML] Pharmacist-initiated pre-emptive pharmacogenetic panel testing with clinical decision support in primary care: record of PGx results and real-world impact

CH van der Wouden, PCD Bank, K Özokcu, JJ Swen… - Genes, 2019 - mdpi.com
Logistics and (cost-) effectiveness of pharmacogenetic (PGx)-testing may be optimized when
delivered through a pre-emptive panel-based approach, within a clinical decision support …

Pharmacogenomic clinical decision support: a scoping review

DM Smith, DT Wake… - Clinical Pharmacology & …, 2023 - Wiley Online Library
Clinical decision support (CDS) is often cited as an essential part of pharmacogenomics
(PGx) implementations. A multitude of strategies are available; however, it is unclear which …

[HTML][HTML] Integrating clinical decision support systems for pharmacogenomic testing into clinical routine-a scoping review of designs of user-system interactions in …

M Hinderer, M Boeker, SA Wagner, M Lablans… - BMC Medical Informatics …, 2017 - Springer
Background Pharmacogenomic clinical decision support systems (CDSS) have the potential
to help overcome some of the barriers for translating pharmacogenomic knowledge into …

The inclusion of health data standards in the implementation of pharmacogenomics systems: a scoping review

D Roosan, A Hwang, AV Law, J Chok… - …, 2020 - Future Medicine
Background: Despite potential benefits, the practice of incorporating pharmacogenomics
(PGx) results in clinical decisions has yet to diffuse widely. In this study, we conducted a …

Implementation of pharmacogenomics in everyday clinical settings

PCD Bank, JJ Swen, HJ Guchelaar - Advances in Pharmacology, 2018 - Elsevier
Currently, germline pharmacogenomics (PGx) is successfully implemented within certain
specialties in clinical care. With the integration of PGx in pharmacotherapy multiple …

[HTML][HTML] Implementation of a pharmacogenomic testing service through community pharmacy in the Netherlands: results from an early service evaluation

T Thornley, B Esquivel, DJ Wright, H Dop, CL Kirkdale… - Pharmacy, 2021 - mdpi.com
Community pharmacy services have evolved to include medical and pharmaceutical
interventions alongside dispensing. While established pharmacogenomic (PGx) testing is …

Implementing pharmacogenetic testing in rural primary care practices: a pilot feasibility study

LG Dressler, GC Bell, PM Abernathy, K Ruch… - …, 2019 - Future Medicine
Aim: Assess feasibility and perspectives of pharmacogenetic testing/PGx in rural, primary
care physician (PCP) practices when PCPs are trained to interpret/apply results and testing …

[HTML][HTML] 3D-printed bioreactors for DNA amplification: Application to companion diagnostics

AK Pantazis, G Papadakis, K Parasyris… - Sensors and Actuators B …, 2020 - Elsevier
The aim of this work is to employ 3D printing for the fabrication of bioreactors for DNA
amplification with the long term aim to use them to healthcare applications. Initially, the most …