Systematic review: probiotics in the management of lower gastrointestinal symptoms–an updated evidence‐based international consensus

APS Hungin, CR Mitchell, P Whorwell… - Alimentary …, 2018 - Wiley Online Library
Background In 2013, a systematic review and Delphi consensus reported that specific
probiotics can benefit adult patients with irritable bowel syndrome (IBS) and other …

The role of the gut microbiome in colonization resistance and recurrent Clostridioides difficile infection

AM Seekatz, N Safdar… - Therapeutic Advances in …, 2022 - journals.sagepub.com
The species composition of the human gut microbiota is related to overall health, and a
healthy gut microbiome is crucial in maintaining colonization resistance against pathogens …

Next-generation probiotics targeting Clostridium difficile through precursor-directed antimicrobial biosynthesis

JK Spinler, J Auchtung, A Brown, P Boonma… - Infection and …, 2017 - Am Soc Microbiol
Integration of antibiotic and probiotic therapy has the potential to lessen the public health
burden of antimicrobial-associated diseases. Clostridium difficile infection (CDI) represents …

Probiotics for Prevention and Treatment of Clostridium difficile Infection

L Valdés-Varela, M Gueimonde… - Updates on Clostridium …, 2018 - Springer
Probiotics have been claimed as a valuable tool to restore the balance in the intestinal
microbiota following a dysbiosis caused by, among other factors, antibiotic therapy. This …

Diagnosis and management of Clostridioides difficile infection in patients with inflammatory bowel disease

RS Dalal, JR Allegretti - Current opinion in gastroenterology, 2021 - journals.lww.com
CDI may complicate the course of IBD, however the presentation may not be typical.
Therefore, all patients with worsening gastrointestinal symptoms should be evaluated for …

[HTML][HTML] A Surface Protein From Lactobacillus plantarum Increases the Adhesion of Lactobacillus Strains to Human Epithelial Cells

G Wang, M Zhang, J Zhao, Y Xia, PFH Lai… - Frontiers in …, 2018 - frontiersin.org
Adhesion to epithelial cells is considered important for Lactobacillus to exert probiotic
effects. In this study, we found that trypsin treatment decreased the adhesion ability of …

Lactobacillus Protects Against S. Typhimurium–Induced Intestinal Inflammation by Determining the Fate of Epithelial Proliferation and Differentiation

X Lu, S Xie, L Ye, L Zhu, Q Yu - Molecular nutrition & food …, 2020 - Wiley Online Library
Scope The influence of the intestinal microbiota, such as Lactobacillus, on the intestinal
mucosa, particularly intestinal stem cells, remains incompletely understood. In this study …

Clostridium difficile Colitis Prevention and Treatment

M Dinleyici, Y Vandenplas - … Diseases and Public Health Volume 10, 2019 - Springer
Clostridium difficile (C. diff) is the most common causative agent of antibiotic-associated
diarrhea and colitis. This spore-forming, obligate anaerobic, gram-positive bacillus is …

Ameliorative effect of probiotics (Lactobacillus paracaseii and Protexin®) and prebiotics (propolis and bee pollen) on clindamycin and propionic acid-induced …

K Aabed, RS Bhat, N Moubayed, M Al-Mutiri… - Cellular and Molecular …, 2019 - cellmolbiol.org
Colonization by toxin-producing bacteria in the gut plays a major role in bowel problems in
autistic patients. Prebiotics can inhibit the growth of these pathogenic microbes by …

[HTML][HTML] Prevention of Clostridium difficile Infection and Associated Diarrhea: An Unsolved Problem

N Principi, M Gnocchi, M Gagliardi, A Argentiero… - Microorganisms, 2020 - mdpi.com
For many years, it has been known that Clostridium difficile (CD) is the primary cause of
health-care-associated infectious diarrhea, afflicting approximately 1% of hospitalized …