[HTML][HTML] Pharmacology and pharmacogenetics of prednisone and prednisolone in patients with nephrotic syndrome
AM Schijvens, R Ter Heine, SN de Wildt… - Pediatric …, 2019 - Springer
Nephrotic syndrome is one of the most common glomerular disorders in childhood.
Glucocorticoids have been the cornerstone of the treatment of childhood nephrotic …
Glucocorticoids have been the cornerstone of the treatment of childhood nephrotic …
[HTML][HTML] Therapeutic trials in difficult to treat steroid sensitive nephrotic syndrome: challenges and future directions
Steroid sensitive nephrotic syndrome is a common condition in pediatric nephrology, and
most children have excellent outcomes. Yet, 50% of children will require steroid-sparing …
most children have excellent outcomes. Yet, 50% of children will require steroid-sparing …
[HTML][HTML] Reverse phenotyping after whole-exome sequencing in steroid-resistant nephrotic syndrome
S Landini, B Mazzinghi, F Becherucci… - Clinical Journal of the …, 2020 - journals.lww.com
Results A total of 111 patients (64 steroid-resistant and 47 steroid-sensitive) were included
in the study. Not a single pathogenic variant was detected in the steroid-sensitive group …
in the study. Not a single pathogenic variant was detected in the steroid-sensitive group …
[HTML][HTML] Clinical significance of T lymphocyte subsets, immunoglobulin and complement expression in peripheral blood of children with steroid-dependent nephrotic …
S Chen, J Wang, S Liang - American journal of translational …, 2021 - ncbi.nlm.nih.gov
Objective: To investigate the clinical significance of T lymphocyte subsets, immunoglobulin
and complement expression in the peripheral blood of children with steroid-dependent …
and complement expression in the peripheral blood of children with steroid-dependent …
Induction prednisone dosing for childhood nephrotic syndrome: how low should we go?
M Sibley, A Roshan, A Alshami, M Catapang… - Pediatric …, 2018 - Springer
Background Historically, children with nephrotic syndrome (NS) across British Columbia
(BC), Canada have been cared for without formal standardization of induction prednisone …
(BC), Canada have been cared for without formal standardization of induction prednisone …
[HTML][HTML] Commentary on “Pediatric Idiopathic Steroid-sensitive Nephrotic Syndrome Diagnosis and Therapy-Short version of the updated German Best Practice …
R Ehren, MR Benz, PT Brinkkötter, J Dötsch… - Pediatric …, 2021 - Springer
Childhood idiopathic nephrotic syndrome is rare but represents the most common
glomerular disease in the pediatric cohort. Glucocorticoid (steroid) treatment depicts the …
glomerular disease in the pediatric cohort. Glucocorticoid (steroid) treatment depicts the …
[HTML][HTML] The Canadian childhood nephrotic syndrome (CHILDNEPH) study: report on mid-study feasibility, recruitment and main measures
Background To assess reasons for continuing practice variation in the management of
childhood nephrotic syndrome despite expert reviews and guidelines, we are conducting a …
childhood nephrotic syndrome despite expert reviews and guidelines, we are conducting a …
[PDF][PDF] The quest for optimal control of relapses in children with nephrotic syndrome
AM Schijvens, R Ehren, LT Weber, MF Schreuder - Kidney Int, 2019 - repository.ubn.ru.nl
In children, the main causes of CKD are congenital diseases and glomerular disorders. CKD
is associated with multiple physiological changes and may therefore influence various PK …
is associated with multiple physiological changes and may therefore influence various PK …
Factors of corticosteroid resistant nephrotic syndrome progression in children
N Zhuravleva, V Buryak, S Horoshev… - BIO Web of …, 2020 - bio-conferences.org
Nephrotic syndrome (NS) is one of the most severe kidney pathologies. NS often relapses
and becomes resistant to immunosuppressive therapy. In order to identify factors that …
and becomes resistant to immunosuppressive therapy. In order to identify factors that …