Fecal microbiota transplantation as a tool to treat and reduce susceptibility to disease in animals

MC Niederwerder - Veterinary immunology and immunopathology, 2018 - Elsevier
Fecal microbiota transplantation (FMT) is the process by which fecal microbiota are donated
from a healthy individual and subsequently transplanted into a diseased or young individual …

Faecal microbiota transplantation for recurrent C. difficile infections: challenges and improvement opportunities for clinical practice and healthcare systems

L Hocking, G Ianiro, RW Leong, T Iqbal… - Alimentary …, 2023 - Wiley Online Library
Background There is growing interest in faecal microbiota transplantation (FMT) as a
treatment for recurrent Clostridioides difficile infection (CDI), but evidence on the diverse …

A standardised model for stool banking for faecal microbiota transplantation: a consensus report from a multidisciplinary UEG working group

JJ Keller, RE Ooijevaar, CL Hvas… - United European …, 2021 - Wiley Online Library
Background Faecal microbiota transplantation is an emerging therapeutic option,
particularly for the treatment of recurrent Clostridioides difficile infection. Stool banks that …

[HTML][HTML] Health economic evaluations comparing faecal microbiota transplantation with antibiotics for treatment of recurrent Clostridioides difficile infection: a …

LH Hammeken, SMD Baunwall, CL Hvas… - Health Economics …, 2021 - Springer
Background Faecal microbiota transplantation (FMT) is increasingly being used in the
treatment of recurrent Clostridioides difficile infection (rCDI). Health economic evaluations …

Microbiome-based therapeutics for Clostridioides difficile infection: helpful solutions or unclear cocktails?

SS Hota, SM Poutanen - The Lancet Infectious Diseases, 2023 - thelancet.com
The past 2 years have brought exciting developments to microbiome-based therapeutics
(MBT)—products derived or prepared from human stool—for recurrent Clostridioides difficile …

[HTML][HTML] Defined microbial communities and their soluble products protect mice from Clostridioides difficile infection

K Douchant, SM He, C Noordhof, J Greenlaw… - Communications …, 2024 - nature.com
Clostridioides difficile is the leading cause of antibiotic-associated infectious diarrhea. The
development of C. difficile infection is tied to perturbations of the bacterial community in the …

Challenges establishing a multi-purpose fecal microbiota transplantation stool donor program in Toronto, Canada

SS Hota, I McNamara, R Jin… - Official Journal of …, 2019 - jammi.utpjournals.press
Background: The success of fecal microbiota transplantation (FMT) programs depends on
maintaining suitable stool donors. We describe challenges recruiting and retaining universal …

Microbiota-Based Live Biotherapeutic Products for Clostridioides Difficile Infection- The Devil is in the Details

L Monday, G Tillotson, T Chopra - Infection and Drug Resistance, 2024 - Taylor & Francis
Clostridioides difficile infection (CDI) remains a significant contributor to healthcare costs
and morbidity due to high rates of recurrence. Currently, available antibiotic treatment …

Overcoming donor variability and risks associated with fecal microbiota transplants through bacteriophage-mediated treatments

TS Rasmussen, X Mao, S Forster, SB Larsen… - bioRxiv, 2023 - biorxiv.org
Background Fecal microbiota transplantation (FMT) and fecal virome transplantation (FVT,
sterile filtrated donor feces) have been effective in treating recurrent Clostridioides difficile …

Specific alterations in mucosa-associated bacterial composition in ulcerative colitis (UC) patients with different degrees of inflammation

Y Shang, Z Zhai, J Huang, L Li… - Biotechnology & …, 2022 - Taylor & Francis
The aim of this study is to evaluate the specific bacterial communities and alterations and to
explore the method predicting the microbiological evolution tendency of ulcerative colitis …