Haematological management of major haemorrhage: a British Society for Haematology guideline

SJ Stanworth, K Dowling, N Curry… - British journal of …, 2022 - Wiley Online Library
Background Major haemorrhage is a clinical emergency that results in morbidity and
mortality: practice guidance is important to reduce these risks. Delayed recognition of …

Hemostatic defects in massive transfusion: an update and treatment recommendations

LM Napolitano - Expert Review of Hematology, 2021 - Taylor & Francis
Introduction Acute hemorrhage is a global healthcare issue, and remains the leading
preventable cause of death in trauma. Acute severe hemorrhage can be related to traumatic …

Massive hemorrhage protocol: a practical approach to the bleeding trauma patient

A Petrosoniak, K Pavenski, LT da Luz… - Emergency Medicine …, 2023 - emed.theclinics.com
A focused assessment with sonography in trauma examination is positive for free fluid in the
right upper quadrant. There is no evidence of pneumothorax on ultrasound. Her pelvis is …

[HTML][HTML] Correction of haemorrhagic shock-associated coagulopathy and impaired haemostasis by plasma, prothrombin complex concentrates or an activated protein …

LJ Eltringham-Smith, SC Meixner, ELG Pryzdial… - Scientific Reports, 2023 - nature.com
Even with extensive transfusion support, trauma-induced bleeding often leads to death.
Early intervention may improve outcomes, yet which blood products, factor concentrates, or …

Guideline No. 431: postpartum hemorrhage and hemorrhagic shock

M Basso, C Chan, K Duckitt, R Lett - Journal of Obstetrics and …, 2022 - Elsevier
Objective This guideline aims to provide evidence for prevention, recognition, and treatment
of postpartum hemorrhage including severe hemorrhage leading to hemorrhagic shock …

Protocol for a multicentre, randomised, parallel-control, superiority trial comparing administration of clotting factor concentrates with a standard massive haemorrhage …

LT da Luz, J Callum, A Beckett, HP Hucke, J Carroll… - BMJ open, 2021 - bmjopen.bmj.com
Introduction Acute traumatic coagulopathy (ATC) in bleeding trauma patients increase in-
hospital mortality. Fibrinogen concentrate (FC) and prothrombin complex concentrate (PCC) …

Development of a national out-of-hospital transfusion protocol: a modified RAND Delphi study

J von Vopelius-Feldt, J Lockwood, S Mal… - … Open Access Journal, 2023 - cmajopen.ca
Background: Early resuscitation with blood components or products is emerging as best
practice in selected patients with trauma and medical patients; as a result, out-of-hospital …

Anaesthesia for vascular emergencies–a state of the art review

N Boucher, H Dreksler, J Hooper, S Nagpal… - …, 2023 - Wiley Online Library
In this state‐of‐the‐art review, we discuss the presenting symptoms and management
strategies for vascular emergencies. Although vascular emergencies are best treated at a …

Canadian tertiary care pediatric massive hemorrhage protocols: a survey and comprehensive national review

V Arsenault, L Lieberman, P Akbari, K Murto… - Canadian Journal of …, 2023 - Springer
Purpose Hemorrhage is the leading cause of pediatric death in trauma and cardiac arrest
during surgery. Adult studies report improved patient outcomes using massive hemorrhage …

[HTML][HTML] Nonsurgical management of major hemorrhage

J Callum, CCD Evans, A Barkun, K Karkouti - CMAJ, 2023 - Can Med Assoc
• Major hemorrhage is a challenging clinical problem that can occur with traumatic injury,
postpartum hemorrhage, major surgery and gastrointestinal bleeding.• A massive …