Storage conditions, sample integrity, interferences, and a decision tool for investigating unusual high-sensitivity cardiac troponin results

MA Lafrenière, V Tandon, C Ainsworth, K Nouri… - Clinical …, 2023 - Elsevier
The current definition of high-sensitivity cardiac troponin (hs-cTn) assays is laboratory-based
and their analytical attributes and characteristics have drawn significant attention in the …

[HTML][HTML] Acute phase response and non-reproducible elevated concentrations with a high-sensitivity cardiac troponin I assay

PA Kavsak, L Clark, J Martin, CT Mark, G Paré… - Journal of Clinical …, 2021 - mdpi.com
High-sensitivity cardiac troponin (hs-cTn) testing has enabled physicians to make earlier
diagnostic and prognostic decisions in the hospital setting than previous cardiac troponin …

[HTML][HTML] Diagnostic performance of serial high-sensitivity cardiac troponin measurements in the emergency setting

PA Kavsak, MK Hewitt, SE Mondoux… - Journal of …, 2021 - mdpi.com
Serial high-sensitivity cardiac troponin (hsTn) testing in the emergency department (ED) and
the intensive cardiac care unit may assist physicians in ruling out or ruling in acute …

[HTML][HTML] Disagreement between cardiac troponin tests yielding a higher incidence of myocardial injury in the emergency setting

PA Kavsak, SE Mondoux, J Martin, MK Hewitt… - Journal of …, 2021 - mdpi.com
Differences in patient classification of myocardial injury between high-sensitivity cardiac
troponin (hs-cTn) assays have largely been attributed to assay design and analytical …

Comparison of the clinical chemistry score to other biomarker algorithms for rapid rule-out of acute myocardial infarction and risk stratification in patients with …

M Yildirim, C Salbach, C Reich, BR Milles… - International Journal of …, 2024 - Elsevier
Background The clinical chemistry score (CCS) comprising high-sensitivity cardiac troponins
(hs-cTn), glucose and estimated glomerular filtration rate has been previously validated with …

[HTML][HTML] The Clinical Validation of a Common Analytical Change Criteria for Cardiac Troponin for Ruling in an Acute Cardiovascular Outcome in Patients Presenting …

PA Kavsak, S Sharif, I Globe, C Ainsworth, J Ma… - Journal of …, 2023 - mdpi.com
Serial cardiac troponin (cTn) testing on patients with symptoms suggestive of acute coronary
syndrome (ACS) is primarily to identify those patients with evolving myocardial injury. With …

High-sensitivity troponin i predicts major cardiovascular events after non-cardiac surgery: a vascular events in non-cardiac surgery patients cohort evaluation (VISION) …

FK Borges, E Duceppe, D Heels-Ansdell… - Clinical …, 2023 - academic.oup.com
Background Myocardial injury after non-cardiac surgery (MINS), based on measurement of
troponin T, is associated with perioperative major adverse cardiovascular events (MACE) …

Sex-specific absolute delta thresholds for high-sensitivity cardiac troponin T

L Liu, W Consagra, X Cai, A Mathias… - Clinical …, 2022 - academic.oup.com
Background Sex differences in high-sensitivity cardiac troponin (hs-cTn) concentrations from
healthy populations have led to the establishment of sex-specific upper reference limits for …

Additive value of bioclinical risk scores to high sensitivity troponins-only strategy in acute coronary syndrome

AM Dupuy, G Pasquier, L Thiebaut, F Roubille… - Clinica Chimica …, 2021 - Elsevier
Background Discharging patients home as quickly as possible, or gaining the ability to
eliminate a serious event is a goal requested by clinicians in the emergency department …

Additional approaches for identifying non-reproducible cardiac troponin results

PA Kavsak - Clinical Chemistry and Laboratory Medicine (CCLM), 2021 - degruyter.com
Medicine have highlighted the impact and prevalence of non-reproducible cardiac troponin
results that are of interest to both clinicians and laboratory professionals alike [1, 2]. Of …