Impairment in ventricular relaxation and preserved left ventricular ejection fraction are the
two main features of heart failure with preserved ejection fraction (HFpEF) a difficult clinical …

Introduction Oral anticoagulants (OACs) prevent stroke in patients with atrial fibrillation (AF).
Several factors may cause OAC switching. Objectives To examine the phenomenon of OAC …

Background Adherence to oral anticoagulants (OACs) in patients with atrial fibrillation (AF) is
important in preventing stroke. The dominance of retrospective studies using administrative …

Although effective and safe, treatment with direct oral anticoagulants (DOAC) in atrial
fibrillation (AF) is still associated with thrombotic complications. Whether the measurement of …

Introduction Proton pump inhibitors (PPIs) are widely used for primary and secondary
prevention of upper gastrointestinal bleeding. However, there remains controversy about the …

Pharmacovigilance is defined by the World Health Organization as “the science and
activities relating to the detection, assessment, understanding and prevention of adverse …

Aims Clinical trials have found differences in bleeding locations between direct oral
anticoagulants (DOAC) and vitamin K antagonists (VKA). The present study was performed …

Introduction Patients with atrial fibrillation (AF) often switch between oral anticoagulants
(OACs). It can be hard to know why a patient has switched outside of a clinical setting …

February 2023 issue of Canadian Family Physician1 encouraging the adoption of team-
based care as one solution to alleviating the current strain on our family physician resources …

ABSTRACT Introduction Proton pump inhibitors (PPIs) are widely used for primary and
secondary prevention of upper gastrointestinal bleeding. However, there remains …