Real-world treatment of hepatitis C with second-generation direct-acting antivirals: initial results from a multicentre Canadian retrospective cohort of diverse patients

AI Aspinall, AA Shaheen, GS Kochaksaraei… - … Open Access Journal, 2018 - cmajopen.ca
Background: High hepatitis C cure rates have been observed in registration trials with
second-generation direct-acting antivirals. Real-world data also indicate high sustained viral …

English hepatitis C registry data show high response rates to directly acting anti‐virals, even if treatment is not completed

K Drysdale, Y Ntuli, J Bestwick… - Alimentary …, 2020 - Wiley Online Library
Summary Background In England, choice of hepatitis C therapy is determined by national
contracts that change with time, facilitating comparisons between different regimens …

Effectiveness, safety and clinical outcomes of direct-acting antiviral therapy in HCV genotype 1 infection: Results from a Spanish real-world cohort

JL Calleja, J Crespo, D Rincón, B Ruiz-Antorán… - Journal of …, 2017 - Elsevier
Background & Aims Clinical trials evaluating second-generation direct-acting antiviral
agents (DAAs) have shown excellent rates of sustained virologic response (SVR) and good …

Effectiveness of second-generation direct-acting antivirals in chronic hepatitis C

R Juanbeltz, JM Zozaya, J Reparaz… - Anales del sistema …, 2017 - europepmc.org
Second-generation direct-acting antivirals (DAA) have shown high sustained virologic
response (SVR) for the treatment of chronic hepatitis C in clinical trials. The objective of this …

Factors associated with treatment failure of direct‐acting antivirals for chronic hepatitis C: a real‐world nationwide hepatitis C virus registry programme in Taiwan

CY Chen, CF Huang, PN Cheng, KC Tseng… - Liver …, 2021 - Wiley Online Library
Background/aims Direct‐acting antivirals (DAAs) are highly effective in treating chronic
hepatitis C virus (HCV)‐infected patients. The real‐world treatment outcome in Taiwanese …

Effectiveness of direct‐acting agents for chronic hepatitis C treatment in South America: A systematic review and meta‐analysis

EC Castro Filho, J Piedade, R Castro… - Journal of Viral …, 2020 - Wiley Online Library
The effectiveness of direct‐acting agents (DAAs) for hepatitis C treatment in limited‐resource
settings remains unclear. We estimated the pooled sustained virological response rates of …

Real‐world experiences with direct‐acting antiviral agents for chronic hepatitis C treatment

KE Daniel, K Saeian, S Rizvi - Journal of Viral Hepatitis, 2020 - Wiley Online Library
As direct‐acting antiviral (DAA) agents become more readily available for the treatment of
chronic hepatitis C, it is important to understand real‐world treatment experiences. In order …

Effectiveness of treatment for hepatitis C virus reinfection following direct acting antiviral therapy in the REACH-C cohort

JM Carson, B Hajarizadeh, J Hanson, J O'Beirne… - International Journal of …, 2021 - Elsevier
Background Direct acting antiviral (DAA) therapy is highly effective for hepatitis C virus
(HCV) infection, but reinfection following treatment may compromise benefits of cure. This …

[HTML][HTML] Real life efficacy and safety of direct-acting antiviral therapy for treatment of patients infected with hepatitis C virus genotypes 1, 2 and 3 in northwest China

Y Yang, FP Wu, WJ Wang, JJ Shi, YP Li… - World journal of …, 2019 - ncbi.nlm.nih.gov
BACKGROUND Regimens involving direct-acting antiviral agents (DAAs) are recommended
for the treatment of infection with hepatitis C virus (HCV) genotypes 1, 2 and 3. But real …

[PDF][PDF] Advances in interferon‐free hepatitis C therapy: 2014 and beyond

S Sarkar, JK Lim - Hepatology, 2014 - Wiley Online Library
Background: Interferon-based treatment is not suitable for many patients with hepatitis C
virus (HCV) infection because of contraindications such as psychiatric illness, and a high …