Background: Canadian health care facilities must report losses or thefts of opioids to Health
Canada. To broaden the understanding of opioid loss in Canada, we analyzed data …

Background High levels of opioid-related mortality, as well as morbidity, contribute to the
excessive opioid-related disease burden in North America, induced by high availability of …

Purpose Population‐based observational studies have documented global increases in
opioid analgesic use. Many studies have used a single population‐adjusted metric (number …

Background Into the 21st century, the conflation of high rates of chronic pain, systemic gaps
in treatment availability and access, and the arrival of potent new opioid medications (eg …

Abstract Background The Canadian opioid crisis is a complex, multifaceted problem
involving prescribed, diverted and illicitly manufactured opioids. This study sought to …

Purpose To explore the determinants of total opioid consumption in a Canadian province,
and to examine patterns of opioid dispensations by sex, age, and income quintile. Methods …

The rise in harms associated with opioids is an issue of increasing public health importance
in Canada. The Government of Canada recently reported 2,816 apparent opioid-related …

Background Canada has experienced a distinctly bifurcated pattern of (strong) opioid
utilization post-2000, with multifold increases rendering it one of the world's highest opioid …

Abstract The United States is enduring a preventable opioid crisis, particularly involving a
population being treated in a hospital setting, a subset of whom may escalate to illicit …

Purpose Although pharmaceutical claims are an essential data source for
pharmacoepidemiological studies, these data potentially under‐estimate opioid utilisation …