The effect of interventions targeting gut microbiota on depressive symptoms: a systematic review and meta-analysis

M Hofmeister, F Clement, S Patten, J Li… - … Open Access Journal, 2021 - cmajopen.ca
Background: Despite their popularity, the efficacy of interventions targeting gut microbiota to
improve depressive symptoms is unknown. Our objective is to summarize the effect of …

[HTML][HTML] Updated review and meta-analysis of probiotics for the treatment of clinical depression: adjunctive vs. stand-alone treatment

VL Nikolova, AJ Cleare, AH Young… - Journal of clinical medicine, 2021 - mdpi.com
Recent years have seen a rapid increase in the use of gut microbiota-targeting interventions,
such as probiotics, for the treatment of psychiatric disorders. The objective of this update …

Effect of prebiotics, probiotics, synbiotics on depression: results from a meta-analysis

Q Zhang, B Chen, J Zhang, J Dong, J Ma, Y Zhang… - BMC psychiatry, 2023 - Springer
Accumulating studies have shown the effects of gut microbiota management tools in
improving depression. We conducted a meta-analysis to evaluate the effects of prebiotics …

Effect of probiotic interventions on depressive symptoms: A narrative review evaluating systematic reviews

I Nadeem, MZ Rahman… - Psychiatry and …, 2019 - Wiley Online Library
Depression is one of the most prevalent mental illnesses and is often associated with
various other medical disorders. Since the 1980s, the primary pharmacological treatment …

Can psychobiotics “mood” ify gut? An update systematic review of randomized controlled trials in healthy and clinical subjects, on anti-depressant effects of probiotics …

E Vaghef-Mehrabany, V Maleki, M Behrooz, F Ranjbar… - Clinical nutrition, 2020 - Elsevier
Background & aims Depression is a major debilitating health problem with high global
prevalence. Gut microbiota dysbiosis might be implicated in pathophysiology of depression …

Acceptability, tolerability, and estimates of putative treatment effects of probiotics as adjunctive treatment in patients with depression: A randomized clinical trial

VL Nikolova, AJ Cleare, AH Young, JM Stone - JAMA psychiatry, 2023 - jamanetwork.com
Importance The microbiota-gut-brain axis is a promising target for novel treatments for mood
disorders, such as probiotics. However, few clinical trials have been conducted, and further …

Gut feeling: Randomized controlled trials of probiotics for the treatment of clinical depression: Systematic review and meta-analysis

V Nikolova, SY Zaidi, AH Young… - Therapeutic …, 2019 - journals.sagepub.com
Background: Recently the gut microbiota has attracted significant interest in psychiatric
research due to the observed bidirectional gut–brain communication. A growing body of …

Effect of probiotic supplementation on gut microbiota in patients with major depressive disorders: a systematic review

QX Ng, YL Lim, CYL Yaow, WK Ng, J Thumboo… - Nutrients, 2023 - mdpi.com
There is accumulating evidence on the beneficial effects of probiotic supplementation for
patients with depressive disorders. However, prior reviews on the topic have largely focused …

[HTML][HTML] The efficacy, safety, and tolerability of probiotics on depression: clinical results from an open-label pilot study

CJK Wallace, RV Milev - Frontiers in psychiatry, 2021 - frontiersin.org
Background: A growing body of research has shown that consumption of probiotics can
improve symptoms associated with mood and anxiety disorders through activity of the gut …

Prebiotics and probiotics for depression and anxiety: A systematic review and meta-analysis of controlled clinical trials

RT Liu, RFL Walsh, AE Sheehan - Neuroscience & Biobehavioral Reviews, 2019 - Elsevier
With growing interest in the gut microbiome, prebiotics and probiotics have received
considerable attention as potential treatments for depression and anxiety. We conducted a …