Background Proton pump inhibitors (PPIs) cause interstitial nephritis and are an
underappreciated cause of acute kidney injury. We examined the risk of acute kidney injury …

Background Proton pump inhibitors (PPI s) have been linked to acute kidney injury (AKI) and
chronic kidney disease (CKD); however, current evidence has only been evaluated in a …

Background Acute interstitial nephritis secondary to proton pump inhibitors (PPIs) frequently
goes undiagnosed due to its subacute clinical presentation, which may later present as …

Background Recent studies have suggested a potential increased risk of acute kidney injury
(AKI) among proton-pump inhibitor (PPI) users. However, the present results are conflicting …

Since their approval by the Food and Drug Administration (FDA) in 1989, proton pump
inhibitors (PPIs) have become one of the most highly utilized drugs in the United States …

Importance Proton pump inhibitors (PPIs) are among the most commonly used drugs
worldwide and have been linked to acute interstitial nephritis. Less is known about the …

Background Proton pump inhibitors (PPI) are a widely-used class of drugs for the treatment
of gastro-esophageal reflux disease and other acid-related disorders of the gastrointestinal …

Proton pump inhibitor (PPI) use is associated with an increased risk of acute kidney injury
(AKI), incident chronic kidney disease (CKD), and progression to end-stage renal disease …

The magnitude of the suspected increase in risk of acute interstitial nephritis among proton
pump inhibitor users is uncertain. Here, we conducted a nested case-control study using …

Background Proton Pump Inhibitors (PPIs) have been associated with chronic kidney
disease (CKD). Our objective was to quantify the association between PPI use and incident …