Drug therapies for chronic hepatitis C infection: a cost-effectiveness analysis

WWL Wong, KM Lee, S Singh, G Wells… - … Open Access Journal, 2017 - cmajopen.ca
Background: Before 2011, pegylated interferon plus ribavirin was the standard therapy for
chronic hepatitis C. Interferon-free direct-acting antiviral agents were then approved …

Cost-effectiveness of treatment for chronic hepatitis C infection in an evolving patient population

JA Salomon, MC Weinstein, JK Hammitt, SJ Goldie - Jama, 2003 - jamanetwork.com
ContextApproximately 2.7 million US individuals are chronically infected with the hepatitis C
virus (HCV). As public health campaigns are pursued, a growing number of treatment …

Costs and outcomes of treating chronic hepatitis C patients in routine care–results from a nationwide multicenter trial

JT Stahmeyer, C Krauth, F Bert… - Journal of Viral …, 2016 - Wiley Online Library
Viral hepatitis is a major public health problem affecting millions of people worldwide. Long‐
term consequences are the development of liver cirrhosis and hepatocellular carcinoma …

[HTML][HTML] Chronic hepatitis C treatment outcomes in low-and middle-income countries: a systematic review and meta-analysis

N Ford, C Kirby, K Singh, EJ Mills… - Bulletin of the World …, 2012 - SciELO Public Health
OBJECTIVE: To assess the effectiveness of treatment for hepatitis C virus (HCV) infection in
low-and middle-income countries and identify factors associated with successful outcomes …

Cost-effectiveness of pegylated interferon and ribavirin for patients with chronic hepatitis C treated in routine clinical practice

M Grishchenko, RD Grieve, MJ Sweeting… - International journal of …, 2009 - cambridge.org
Objectives: This study assesses whether pegylated interferon and ribavirin is cost-effective
compared with no antiviral treatment provided in routine clinical practice, for different patient …

Health benefits of antiviral therapy for mild chronic hepatitis C: randomised controlled trial and economic evaluation.

M Wright, R Grieve, J Roberts… - Health technology …, 2006 - researchonline.lshtm.ac.uk
OBJECTIVES: To determine whether combined therapy with interferon-alpha and ribavirin
was more effective and cost-effective than no treatment for patients with mild chronic …

[HTML][HTML] The impact of the new antiviral regimens on patient reported outcomes and health economics of patients with chronic hepatitis C

Z Younossi, L Henry - Digestive and Liver Disease, 2014 - Elsevier
Hepatitis C is an important cause of chronic liver disease worldwide with an estimated 170
million people infected. Hepatitis C virus (HCV)-infected patients are physically and mentally …

Treatment options for patients with hepatitis C: role of pharmacists in optimizing treatment response and managing adverse events

JP Smith - … : The Journal of Human Pharmacology and Drug …, 2008 - Wiley Online Library
Chronic hepatitis C is associated with substantial morbidity and mortality and poses a
considerable socioeconomic burden. Improved treatment regimens, including the standard …

Interferon-free regimens for chronic hepatitis C: barriers due to treatment candidacy and insurance coverage

M Stepanova, ZM Younossi - Digestive diseases and sciences, 2015 - Springer
Background Recently developed interferon-and ribavirin-free regimens to treat hepatitis C
virus infection (HCV) have low side effect profile accompanied by high efficacy. Aim To …

Transitioning to highly effective therapies for the treatment of chronic hepatitis C virus infection: a policy statement and implementation guideline

DJ Smyth, D Webster, L Barrett, M MacMillan… - Canadian Journal of …, 2014 - hindawi.com
Chronic hepatitis C virus (HCV) infection increases all-cause mortality, rates of cirrhosis,
hepatocellular carcinoma, liver transplantation and overall health care utilization. Morbidity …