Background: Current Canadian guidelines suggest that neonatal Bacille Calmette-Guérin
(BCG) vaccination does not result in false-positive tuberculosis (TB) skin tests, despite a …

Rationale: Interferon-γ (IFN-γ) release assays are widely used to diagnose latent infection
with Mycobacterium tuberculosis in adults, but their performance in children remains …

Background The tuberculin skin test (TST) is the most useful method for the diagnosis of
tuberculosis (TB). There is no evidence about the effect of bacillus Calmette–Guerin (BCG) …

Background The tuberculin skin test (TST) has a low specificity in the setting of bacille
Calmette-Guérin (BCG) vaccination. Interferon-γ release assays (IGRAs) appear to be more …

Background: The tuberculin skin test (TST) is often used to screen for latent tuberculosis
infection (LTBI) in school children, many of whom were bacille Calmette-Guérin (BCG) …

Background: Interferon-γ release assays (IGRAs) offer the possibility of improved detection
of latent tuberculosis infection (LTBI). Objective: To analyze discordant tuberculin skin …

Aim The aim of this study was to assist clinicians evaluating refugee children for latent
tuberculosis infection (LTBI) by comparing paired tuberculin skin test (TST) and Quantiferon …

Background Following exposure to TB, contacts are screened to target preventive treatment
at those at high risk of developing TB. The UK has recently revised its recommendations for …

Background The roles of the tuberculin skin test (TST) and QuantiFERON®-TB Gold In-Tube
assay (QFT-IT) in the diagnosis of active tuberculosis (TB) are not clear in young adults. We …

Background: Diagnosis of latent tuberculosis infection is a problem in children because of
lack of a diagnostic standard and potential impact of previous Bacille Calmette–Guérin …