RT Journal Article SR Electronic T1 Racial disparities in COVID-19 vaccination in Canada: results from the cross-sectional Canadian Community Health Survey JF CMAJ Open JO CMAJ FD Canadian Medical Association SP E1075 OP E1082 DO 10.9778/cmajo.20230026 VO 11 IS 6 A1 Guay, Mireille A1 Maquiling, Aubrey A1 Chen, Ruoke A1 Lavergne, Valérie A1 Baysac, Donalyne-Joy A1 Dubé, Ève A1 MacDonald, Shannon E. A1 Driedger, S. Michelle A1 Gilbert, Nicolas L. YR 2023 UL http://www.cmajopen.ca/content/11/6/E1075.abstract AB Background: Racial and ethnic disparities in COVID-19 vaccination coverage have been observed in Canada and in other countries. We aimed to compare vaccination coverage for at least 1 dose of a COVID-19 vaccine between First Nations people living off reserve and Métis, Black, Arab, Chinese, South Asian and White people.Methods: We used data collected between June 2021 and June 2022 by Statistics Canada’s Canadian Community Health Survey, a large, nationally representative cross-sectional study. The analysis included 64 722 participants aged 18 years or older from the 10 provinces. We used a multiple logistic regression model to determine associations between vaccination status and race, controlling for collection period, region of residence, age, gender and education.Results: Nonvaccination against COVID-19 was more frequent in off-reserve First Nations people (adjusted odds ratio [OR] 1.8, 95% confidence interval [CI] 1.2–2.7) and Black people (adjusted OR 1.7, 95% CI 1.1–2.6), and less frequent among South Asian people (adjusted OR 0.3, 95% CI 0.1–0.7) compared to White people.Interpretation: This analysis showed significant inequalities in COVID-19 vaccine uptake between racial/ethnic populations in Canada. Further research is needed to understand the sociocultural, structural and systemic facilitators of and barriers to vaccination across racial groups, and to identify strategies that may improve vaccination uptake among First Nations and Black people.