Predictors of a positive result of the interferon-γ release assay (QuantiFERON-TB Gold)
| Characteristic | IGRA result; no. (%) of children | OR (95% CI) | ||
|---|---|---|---|---|
| Negative n = 152 | Positive n = 24 | Univariate analysis | Multiple logistic regression | |
| Age at first visit, yr | ||||
| ≤ 10 | 91 (59.9) | 10 (42) | Reference | – |
| 11–17 | 61 (40.1) | 14 (58) | 0.48 (0.20–1.15) | – |
| Continuous (older) | – | – | – | 2.98 (1.24–8.30) |
| Age at treatment, yr | ||||
| ≤ 4 | 76 (50.0) | 9 (38) | 2.81 (1.07–7.43) | – |
| 5–16 | 33 (21.7) | 11 (46) | Reference | – |
| Known tuberculosis contact | ||||
| No | 138 (90.8) | 16 (67) | Reference | Reference |
| Yes | 14 (9.2) | 8 (33) | 4.93 (1.79–13.55) | 5.97 (2.06–17.52) |
| Abnormal chest radiograph* | ||||
| No | 132 (86.8) | 20 (83) | Reference | – |
| Yes | 20 (13.2) | 4 (17) | 0.76 (0.23–2.45) | – |
| Prior treatment | ||||
| No | 42 (27.6) | 4 (17) | Reference | – |
| Yes | 110 (72.4) | 20 (83) | 1.91 (0.61, 5.91) | – |
Note: CI = confidence interval, IGRA = interferon-γ release assay, OR = odds ratio.
↵* On second review.