Ataxia-telangiectasia mutated (ATM) is a serine/threonine protein kinase with a master
regulatory function in the DNA damage response. In this role, ATM commands a complex …

… Siavash Zarezadeh and Fintan Stanley analyzed all data. Aaron Goodarzi and Fintan
Stanley drafted the manuscript and figures. All of the authors participated in outreach to general …

The protein and DNA complex known as chromatin is a dynamic structure, adapting to alter
the spatial arrangement of genetic information within the nucleus to meet the ever changing …

Human-made buildings can artificially concentrate radioactive radon gas of geologic origin,
exposing occupants to harmful alpha particle radiation emissions that damage DNA and …

High linear energy transfer (LET) ionising radiation (IR) such as radon-derived alpha particles
and high mass, high energy (HZE) particles of cosmic radiation are the predominant forms …

Cell survival after oxidative DNA damage requires signaling, repair and transcriptional
events often enabled by nucleosome displacement, exchange or removal by chromatin …

Ethics review of research involving humans has become something of an institution in
recent years. It is intended to protect participants from harm and, to that end, follows rigorous …

Ionizing radiation (IR) is environmentally prevalent and, depending on dose and linear
energy transfer (LET), can elicit serious health effects by damaging DNA. Relative to low LET …

Background: Radon (222 Rn) gas is a naturally occurring radioactive isotope arising from
uranium decay in soil and bedrock, escaping and often concentrating in indoor air. Radon …

… Moore S, Stanley FKT, Goodarzi AA. The repair of environmentally relevant DNA double strand
… of the thesis is original, unpublished, independent work by the author, Fintan KT Stanley …