User profiles for Larry D. Lynd

Larry Lynd

Professor, Epidemiology, University of British Columbia
Verified email at ubc.ca
Cited by 8200

Antibiotic use in children is associated with increased risk of asthma

F Marra, CA Marra, K Richardson, LD Lynd… - …, 2009 - publications.aap.org
BACKGROUND. Antibiotic exposure in early childhood is a possible contributor to the increasing
asthma prevalence in industrialized countries. Although a number of published studies …

Selective serotonin-reuptake inhibitor–induced movement disorders

PE Gerber, LD Lynd - Annals of Pharmacotherapy, 1998 - journals.sagepub.com
OBJECTIVE: To compile and evaluate all available data suggesting an association between
selective serotonin-reuptake inhibitor (SSRI) administration and the occurrence of …

Use of interrupted time series methods in the evaluation of health system quality improvement interventions: a methodological systematic review

C Hategeka, H Ruton, M Karamouzian, LD Lynd… - BMJ global …, 2020 - gh.bmj.com
Background When randomisation is not possible, interrupted time series (ITS) design has
increasingly been advocated as a more robust design to evaluating health system quality …

Double trouble: impact of inappropriate use of asthma medication on the use of health care resources

AH Anis, LD Lynd, X Wang, G King, JJ Spinelli… - Cmaj, 2001 - Can Med Assoc
Background: There is considerable controversy about the regular use of short- acting β-agonists
for the treatment of asthma. Although case–control studies have suggested that …

Inadequate statistical power to detect clinically significant differences in adverse event rates in randomized controlled trials

R Tsang, L Colley, LD Lynd - Journal of clinical epidemiology, 2009 - Elsevier
OBJECTIVE: To determine the statistical power to detect potentially clinically significant
differences in serious adverse events between drug therapies reported in a sample of …

[HTML][HTML] The composition and capacity of the clinical genetics workforce in high-income countries: a scoping review

…, A Nisselle, G Study, AM Elliott, LD Lynd - Genetics in …, 2020 - Elsevier
As genetics becomes increasingly integrated into all areas of health care and the use of
complex genetic tests continues to grow, the clinical genetics workforce will likely face greatly …

Patient preferences and experiences of CPAP and oral appliances for the treatment of obstructive sleep apnea: a qualitative analysis

FR Almeida, N Henrich, C Marra, LD Lynd, AA Lowe… - Sleep and …, 2013 - Springer
Objectives The aim of this study is to better understand patients’ perspectives and preferences
about treatment with continuous positive airway pressure (CPAP) and oral appliance (OA) …

[HTML][HTML] The impact of inappropriate use of short acting beta agonists in asthma

JM FitzGerald, H Tavakoli, LD Lynd, K Al Efraij… - Respiratory …, 2017 - Elsevier
Background Inappropriate use of short-acting beta-agonists (SABA) has been associated with
increased morbidity and mortality in asthma. However, the extent and pattern of SABA use …

[HTML][HTML] The cost and diagnostic yield of exome sequencing for children with suspected genetic disorders: a benchmarking study

…, TN Nelson, C du Souich, JM Friedman, LD Lynd - Genetics in …, 2018 - Elsevier
Purpose This study aimed to generate benchmark estimates for the cost, diagnostic yield,
and cost per positive diagnosis of diagnostic exome sequencing (ES) in heterogeneous …

Sumatriptan contraindications and the serotonin syndrome

DM Gardner, LD Lynd - Annals of Pharmacotherapy, 1998 - journals.sagepub.com
… Comme il ya peu d'informations entourant l'utilisation concomitante du sumatriptan et des
IMAO, les auteurs suggèrent qu'il serait prudent d'éviter cette association jusqu'à ce que des …