The risk of pancreatitis with sitagliptin therapy in older adults: a population-based cohort study

KK Clemens, E McArthur, JL Fleet, I Hramiak… - … Open Access Journal, 2015 - cmajopen.ca
Background The risk of pancreatitis with sitagliptin use in routine care remains to be
established in older patients. We aimed to determine this risk in older adults who were newly …

Sitagliptin increases acute pancreatitis risk within 2 years of its initiation: a retrospective cohort analysis of the National Health Insurance database in Taiwan

CH Tseng - Annals of medicine, 2015 - Taylor & Francis
Purpose To evaluate the risk of acute pancreatitis hospitalization with sitagliptin use in
patients with type 2 diabetes mellitus (T2DM). Methods This retrospective cohort analysis …

Safety of sitagliptin in elderly patients with type 2 diabetes: a pooled analysis of 25 clinical studies

EM Round, SS Engel, GT Golm, MJ Davies… - Drugs & aging, 2014 - Springer
Objective The aim of this study was to evaluate the safety and tolerability of sitagliptin 100
mg/day in elderly patients with type 2 diabetes. Design A post hoc pooled analysis of 25 …

Assessing the safety of sitagliptin in older participants in the Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS)

MA Bethel, SS Engel, JB Green, Z Huang… - Diabetes …, 2017 - Am Diabetes Assoc
OBJECTIVE Limited data exist regarding safety and efficacy of antihyperglycemic drugs in
older patients with type 2 diabetes. The Trial Evaluating Cardiovascular Outcomes with …

Sitagliptin use and risk of acute pancreatitis in type 2 diabetes mellitus: a population-based case-control study in Taiwan

KF Liao, CL Lin, SW Lai, WC Chen - European Journal of Internal Medicine, 2016 - Elsevier
Background There is still lack of definite evidence to establish the association between
sitagliptin use and acute pancreatitis. The study aimed to test this issue in Taiwan. Methods …

A comparison of glycaemic effects of sitagliptin and sulfonylureas in elderly patients with type 2 diabetes mellitus

RR Shankar, L Xu, GT Golm, EA O'Neill… - … Journal of Clinical …, 2015 - Wiley Online Library
Introduction In the USA, 45% of patients with type 2 diabetes mellitus (T2 DM) are elderly (≥
65 years old). In general, use of sulfonylurea increases with patient age as does the …

Recent trends in the characteristics of patients prescribed sitagliptin and other oral antihyperglycaemic agents in a large US claims database

KG Brodovicz, TD Kou, CM Alexander… - … Journal of Clinical …, 2013 - Wiley Online Library
Aim This study was designed to determine if differences in baseline characteristics of
patients with type 2 diabetes mellitus (T2DM) being treated with sitagliptin vs. other oral …

Efficacy and safety of sitagliptin in elderly patients with type 2 diabetes mellitus: a focus on hypoglycemia

M Fukuda, K Doi, M Sugawara… - Journal of diabetes …, 2019 - Wiley Online Library
Abstract Aims/Introduction To investigate the efficacy and safety of sitagliptin in elderly
patients with type 2 diabetes mellitus, with a focus on hypoglycemia. Materials and Methods …

[HTML][HTML] Efficacy and safety of adding sitagliptin in type 2 diabetes patients on insulin: Age-Stratified comparison at one year in the ASSIST-K study

M Takai, M Ishikawa, H Maeda… - Journal of Clinical …, 2019 - ncbi.nlm.nih.gov
Background Sitagliptin, the first dipeptidyl peptidase-4 inhibitor, has demonstrated efficacy
and safety as monotherapy and as add-on therapy to oral antidiabetic agents or insulin …

Two-year assessment of the efficacy and safety of sitagliptin in elderly patients with type 2 diabetes: Post hoc analysis of the ASSET-K study

S Umezawa, A Kubota, H Maeda, A Kanamori… - BMC Endocrine …, 2015 - Springer
Background There have only been a few reports about use of dipeptidyl peptidase 4 (DPP-
4) inhibitors in elderly patients with type 2 diabetes mellitus (T2DM), suggesting that the …